3cz3: Difference between revisions

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[[Image:3cz3.png|left|200px]]


{{STRUCTURE_3cz3|  PDB=3cz3  |  SCENE=  }}
==Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA==
 
<StructureSection load='3cz3' size='340' side='right'caption='[[3cz3]], [[Resolution|resolution]] 3.23&Aring;' scene=''>
===Crystal structure of Tomato Aspermy Virus 2b in complex with siRNA===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3cz3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Tomato_aspermy_virus Tomato aspermy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3CZ3 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.23&#8491;</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3cz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cz3 OCA], [https://pdbe.org/3cz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3cz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3cz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3cz3 ProSAT]</span></td></tr>
[[3cz3]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Tomato_aspermy_virus Tomato aspermy virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3CZ3 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/2B_TAV 2B_TAV] Acts as suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Forms a homodimer to measure siRNA duplex in a length-preferencemode. Binds to both siRNA duplexes (19bp) and long siRNA duplexes (30bp).<ref>PMID:10329615</ref> <ref>PMID:8291242</ref> <ref>PMID:9010309</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/3cz3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3cz3 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Tomato aspermy virus]]
[[Category: Tomato aspermy virus]]
[[Category: Ding, S W.]]
[[Category: Ding SW]]
[[Category: Li, F.]]
[[Category: Li F]]
[[Category: Ma, J B.]]
[[Category: Ma JB]]
[[Category: Patel, D J.]]
[[Category: Patel DJ]]
[[Category: Nucleus]]
[[Category: Protein-dsrna complex]]
[[Category: Suppressor of rna silencing]]
[[Category: Viral protein-rna complex]]
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