2r0d: Difference between revisions
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==Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor== | |||
<StructureSection load='2r0d' size='340' side='right'caption='[[2r0d]], [[Resolution|resolution]] 2.04Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2r0d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R0D FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4IP:INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE'>4IP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r0d OCA], [https://pdbe.org/2r0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r0d RCSB], [https://www.ebi.ac.uk/pdbsum/2r0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r0d ProSAT]</span></td></tr> | ||
[[2r0d]] is a 2 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/CYH3_MOUSE CYH3_MOUSE] Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP.<ref>PMID:18042453</ref> | ||
< | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r0/2r0d_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r0d ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Cronin | [[Category: Cronin TC]] | ||
[[Category: Czech | [[Category: Czech MP]] | ||
[[Category: Delprato | [[Category: Delprato A]] | ||
[[Category: DiNitto | [[Category: DiNitto JP]] | ||
[[Category: Gabe Lee MT]] | |||
[[Category: Guilherme A]] | |||
[[Category: Huang S]] | |||
[[Category: Lee | [[Category: Lambright DG]] | ||
[[Category: | |||
[[Category: | |||
[[Category: | |||
Latest revision as of 09:19, 21 February 2024
Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor
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