2r1j: Difference between revisions
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==Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T== | |||
<StructureSection load='2r1j' size='340' side='right'caption='[[2r1j]], [[Resolution|resolution]] 1.53Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2r1j]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_virus_P22 Salmonella virus P22]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R1J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.53Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r1j OCA], [https://pdbe.org/2r1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r1j RCSB], [https://www.ebi.ac.uk/pdbsum/2r1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r1j ProSAT]</span></td></tr> | |||
== | </table> | ||
[[2r1j]] is a 4 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/RPC2_BPP22 RPC2_BPP22] This protein allows the phage to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein C2 to the OR and OL operators, preventing transcription of proteins necessary for lytic development. | |||
== | == Evolutionary Conservation == | ||
< | [[Image:Consurf_key_small.gif|200px|right]] | ||
[[ | Check<jmol> | ||
[[ | <jmolCheckbox> | ||
[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r1/2r1j_consurf.spt"</scriptWhenChecked> | ||
[[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
[ | </jmolCheckbox> | ||
[[Category: | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r1j ConSurf]. | ||
[[Category: | <div style="clear:both"></div> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Salmonella virus P22]] | ||
[[Category: | [[Category: Hsiao C]] | ||
[[Category: Koudelka GB]] | |||
[[Category: Watkins D]] | |||
[[Category: Williams LD]] | |||
[[Category: Woods K]] | |||
Latest revision as of 09:19, 21 February 2024
Crystal Structure of the P22 c2 Repressor protein in complex with the synthetic operator 9T
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