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[[Image:2ugi.png|left|200px]]


{{STRUCTURE_2ugi|  PDB=2ugi  |  SCENE=  }}
==PROTEIN MIMICRY OF DNA FROM CRYSTAL STRUCTURES OF THE URACIL GLYCOSYLASE INHIBITOR PROTEIN AND ITS COMPLEX WITH ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE==
 
<StructureSection load='2ugi' size='340' side='right'caption='[[2ugi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
===PROTEIN MIMICRY OF DNA FROM CRYSTAL STRUCTURES OF THE URACIL GLYCOSYLASE INHIBITOR PROTEIN AND ITS COMPLEX WITH ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2ugi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_phage_PBS2 Bacillus phage PBS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UGI FirstGlance]. <br>
{{ABSTRACT_PUBMED_10080896}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ugi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ugi OCA], [https://pdbe.org/2ugi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ugi RCSB], [https://www.ebi.ac.uk/pdbsum/2ugi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ugi ProSAT]</span></td></tr>
[[2ugi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_phage_pbs2 Bacillus phage pbs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UGI OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/UNGI_BPPB2 UNGI_BPPB2] This protein binds specifically and reversibly to the host uracil-DNA glycosylase, preventing removal of uracil residues from PBS2 DNA by the host uracil-excision repair system.


==See Also==
==See Also==
*[[Uracil glycosylate inhibitor|Uracil glycosylate inhibitor]]
*[[Uracil glycosylase inhibitor|Uracil glycosylase inhibitor]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010080896</ref><references group="xtra"/>
[[Category: Bacillus phage PBS2]]
[[Category: Bacillus phage pbs2]]
[[Category: Large Structures]]
[[Category: Arvai, A S.]]
[[Category: Arvai AS]]
[[Category: Mol, C D.]]
[[Category: Mol CD]]
[[Category: Putnam, C D.]]
[[Category: Putnam CD]]
[[Category: Tainer, J A.]]
[[Category: Tainer JA]]
[[Category: Hydrolase inhibitor]]
[[Category: Protein inhibitor]]
[[Category: Protein mimicry of dna]]

Latest revision as of 06:33, 3 April 2024

PROTEIN MIMICRY OF DNA FROM CRYSTAL STRUCTURES OF THE URACIL GLYCOSYLASE INHIBITOR PROTEIN AND ITS COMPLEX WITH ESCHERICHIA COLI URACIL-DNA GLYCOSYLASE

2ugi, resolution 2.20Å

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