2rg2: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
m Protected "2rg2" [edit=sysop:move=sysop]
OCA (talk | contribs)
No edit summary
 
(5 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:2rg2.png|left|200px]]


{{STRUCTURE_2rg2|  PDB=2rg2  |  SCENE=  }}
==Crystal structure of variant R18L of conjugated bile acid hydrolase from Clostridium perfringens==
 
<StructureSection load='2rg2' size='340' side='right'caption='[[2rg2]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal structure of variant R18L of conjugated bile acid hydrolase from Clostridium perfringens===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2rg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RG2 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[2rg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RG2 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rg2 OCA], [https://pdbe.org/2rg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rg2 RCSB], [https://www.ebi.ac.uk/pdbsum/2rg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rg2 ProSAT]</span></td></tr>
[[Category: Choloylglycine hydrolase]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBH_CLOPE CBH_CLOPE] The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rg/2rg2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rg2 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Clostridium perfringens]]
[[Category: Clostridium perfringens]]
[[Category: Rossmann, M.]]
[[Category: Large Structures]]
[[Category: Saenger, W.]]
[[Category: Rossmann M]]
[[Category: Amidase]]
[[Category: Saenger W]]
[[Category: Bile salt hydrolase]]
[[Category: Bsh]]
[[Category: Cbah]]
[[Category: Choloylglycine hydrolase]]
[[Category: Conjugated bile acid hydrolase]]
[[Category: Hydrolase]]
[[Category: Ntn-hydrolase]]

Latest revision as of 05:29, 17 October 2024

Crystal structure of variant R18L of conjugated bile acid hydrolase from Clostridium perfringens

2rg2, resolution 1.80Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA