2qt5: Difference between revisions

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[[Image:2qt5.png|left|200px]]


{{STRUCTURE_2qt5|  PDB=2qt5  |  SCENE=  }}
==Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide==
 
<StructureSection load='2qt5' size='340' side='right'caption='[[2qt5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
===Crystal Structure of GRIP1 PDZ12 in Complex with the Fras1 Peptide===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2qt5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QT5 FirstGlance]. <br>
{{ABSTRACT_PUBMED_18155042}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qt5 OCA], [https://pdbe.org/2qt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qt5 RCSB], [https://www.ebi.ac.uk/pdbsum/2qt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qt5 ProSAT]</span></td></tr>
[[2qt5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QT5 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/GRIP1_RAT GRIP1_RAT] May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons.<ref>PMID:9069286</ref>  
<ref group="xtra">PMID:018155042</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qt/2qt5_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qt5 ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Feng, W.]]
[[Category: Feng W]]
[[Category: Long, J.]]
[[Category: Long J]]
[[Category: Wei, Z.]]
[[Category: Wei Z]]
[[Category: Zhang, M.]]
[[Category: Zhang M]]
[[Category: Zhao, Y.]]
[[Category: Zhao Y]]
[[Category: Cell junction]]
[[Category: Endoplasmic reticulum]]
[[Category: Membrane]]
[[Category: Pdz tandem]]
[[Category: Pdz-peptide complex]]
[[Category: Peptide binding protein]]
[[Category: Postsynaptic cell membrane]]
[[Category: Protein binding]]
[[Category: Synapse]]