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[[Image:2rla.png|left|200px]]


{{STRUCTURE_2rla| PDB=2rla | SCENE= }}
==ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION==
<StructureSection load='2rla' size='340' side='right'caption='[[2rla]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2rla]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RLA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RLA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rla FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rla OCA], [https://pdbe.org/2rla PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rla RCSB], [https://www.ebi.ac.uk/pdbsum/2rla PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rla ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ARGI1_RAT ARGI1_RAT]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/2rla_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rla ConSurf].
<div style="clear:both"></div>


===ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION===
==See Also==
 
*[[Arginase 3D structures|Arginase 3D structures]]
{{ABSTRACT_PUBMED_9265637}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[2rla]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RLA OCA].
 
==Reference==
<ref group="xtra">PMID:009265637</ref><references group="xtra"/>
[[Category: Arginase]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Christianson, D W.]]
[[Category: Christianson DW]]
[[Category: Kanyo, Z F.]]
[[Category: Kanyo ZF]]
[[Category: Scolnick, L R.]]
[[Category: Scolnick LR]]
[[Category: Arginine metabolism]]
[[Category: Hydrolase]]
[[Category: Urea cycle]]
Retrieved from "https://proteopedia.org/2rla"