2rf8: Difference between revisions

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[[Image:2rf8.png|left|200px]]


{{STRUCTURE_2rf8|  PDB=2rf8  |  SCENE=  }}
==Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens==
 
<StructureSection load='2rf8' size='340' side='right'caption='[[2rf8]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
===Crystal Structure of the mutant C2A conjugated bile acid hydrolase from Clostridium perfringens===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2rf8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RF8 FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
[[2rf8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_perfringens Clostridium perfringens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RF8 OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rf8 OCA], [https://pdbe.org/2rf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rf8 RCSB], [https://www.ebi.ac.uk/pdbsum/2rf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rf8 ProSAT]</span></td></tr>
[[Category: Choloylglycine hydrolase]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBH_CLOPE CBH_CLOPE] The enzyme catalyzes the degradation of conjugated bile acids in the mammalian gut.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rf8_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rf8 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Clostridium perfringens]]
[[Category: Clostridium perfringens]]
[[Category: Rossmann, M.]]
[[Category: Large Structures]]
[[Category: Saenger, W.]]
[[Category: Rossmann M]]
[[Category: Bile salt hydrolase]]
[[Category: Saenger W]]
[[Category: Bsh]]
[[Category: Cbah]]
[[Category: Choloylglycine hydrolase]]
[[Category: Hydrolase]]
[[Category: Ntn-hydrolase]]
Retrieved from "https://proteopedia.org/2rf8"