3ag7: Difference between revisions

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[[Image:3ag7.png|left|200px]]


{{STRUCTURE_3ag7| PDB=3ag7 | SCENE= }}
==An auxilin-like J-domain containing protein, JAC1 J-domain==
<StructureSection load='3ag7' size='340' side='right'caption='[[3ag7]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3ag7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AG7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ag7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ag7 OCA], [https://pdbe.org/3ag7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ag7 RCSB], [https://www.ebi.ac.uk/pdbsum/3ag7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ag7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/JAC1_ARATH JAC1_ARATH] Required for chloroplast photorelocation movement; chloroplast accumulation upon low blue light and for chloroplast movement to the bottom of cells in darkness, by modulating chloroplast actin (Cp-actin) filaments distribution, appearance and disappearance. May mediate a slight resistance to aluminum in root hair cells.<ref>PMID:16113208</ref> <ref>PMID:17150990</ref> <ref>PMID:20562448</ref> <ref>PMID:21737483</ref>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
An auxilin-like J-domain-containing protein, JAC1, is necessary for chloroplast movement in Arabidopsis thaliana, to capture photosynthetic light efficiently under weak light conditions. Here, we performed crystallographic and functional analyses of the J-domain of JAC1. The crystal structure of the J-domain is quite similar to that of bovine auxilin, and possesses a similar positively charged surface, which probably forms the interface with the Hsp70 chaperone. The mutation of the highly conserved HPD motif of the JAC1 J-domain abrogated the chloroplast photorelocation response. These results suggest that the requirement of JAC1 in chloroplast photorelocation movement is attributable to the J-domain's cochaperone activity.


===An auxilin-like J-domain containing protein, JAC1 J-domain===
Crystallographic and functional analyses of J-domain of JAC1 essential for chloroplast photorelocation movement in Arabidopsis thaliana.,Takano A, Suetsugu N, Wada M, Kohda D Plant Cell Physiol. 2010 Aug;51(8):1372-6. Epub 2010 Jun 20. PMID:20562448<ref>PMID:20562448</ref>


{{ABSTRACT_PUBMED_20562448}}
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
</div>
==About this Structure==
<div class="pdbe-citations 3ag7" style="background-color:#fffaf0;"></div>
[[3ag7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AG7 OCA].
== References ==
 
<references/>
==Reference==
__TOC__
<ref group="xtra">PMID:020562448</ref><references group="xtra"/>
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Takano, A.]]
[[Category: Large Structures]]
[[Category: An auxilin-like j-domain containing protein]]
[[Category: Takano A]]
[[Category: Chloroplast accumulation response]]
[[Category: J-domain]]
[[Category: Jac1]]
[[Category: Plant protein]]