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[[Image:2zop.png|left|200px]]


{{STRUCTURE_2zop|  PDB=2zop  |  SCENE=  }}
==X-ray crystal structure of a CRISPR-associated Cmr5 family protein from Thermus thermophilus HB8==
 
<StructureSection load='2zop' size='340' side='right'caption='[[2zop]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===X-ray crystal structure of a CRISPR-associated Cmr5 family protein from Thermus thermophilus HB8===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2zop]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZOP FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[2zop]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZOP OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zop OCA], [https://pdbe.org/2zop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zop RCSB], [https://www.ebi.ac.uk/pdbsum/2zop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zop ProSAT], [https://www.topsan.org/Proteins/RSGI/2zop TOPSAN]</span></td></tr>
 
</table>
==Reference==
== Function ==
<ref group="xtra">PMID:019173314</ref><references group="xtra"/>
[https://www.uniprot.org/uniprot/CMR5_THET8 CMR5_THET8] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Part of the Cmr ribonucleoprotein complex (By similarity).
[[Category: Thermus thermophilus hb8]]
== Evolutionary Conservation ==
[[Category: Agari, Y.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Kuramitsu, S.]]
Check<jmol>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
  <jmolCheckbox>
[[Category: Sakamoto, K.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zo/2zop_consurf.spt"</scriptWhenChecked>
[[Category: Shinkai, A.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Yokoyama, S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: All alpha protein]]
  </jmolCheckbox>
[[Category: National project on protein structural and functional analyse]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zop ConSurf].
[[Category: Nppsfa]]
<div style="clear:both"></div>
[[Category: Riken structural genomics/proteomics initiative]]
__TOC__
[[Category: Rsgi]]
</StructureSection>
[[Category: Structural genomic]]
[[Category: Large Structures]]
[[Category: Unknown function]]
[[Category: Thermus thermophilus HB8]]
[[Category: Agari Y]]
[[Category: Kuramitsu S]]
[[Category: Sakamoto K]]
[[Category: Shinkai A]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/2zop"