2r70: Difference between revisions
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==Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.== | |||
<StructureSection load='2r70' size='340' side='right'caption='[[2r70]], [[Resolution|resolution]] 2.70Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2r70]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Infectious_bursal_disease_virus Infectious bursal disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R70 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R70 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r70 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r70 OCA], [https://pdbe.org/2r70 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r70 RCSB], [https://www.ebi.ac.uk/pdbsum/2r70 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r70 ProSAT]</span></td></tr> | |||
== | </table> | ||
[[2r70]] is a 1 chain structure with sequence from [ | == Function == | ||
[https://www.uniprot.org/uniprot/RDRP_IBDV RDRP_IBDV] RNA-dependent RNA polymerase which is found both free and covalently attached to the genomic RNA. May also contain guanylyl and methyl transferase activities (By similarity). | |||
== | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | |||
[[ | Check<jmol> | ||
[ | <jmolCheckbox> | ||
[ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r70_consurf.spt"</scriptWhenChecked> | ||
[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
[ | </jmolCheckbox> | ||
[[ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r70 ConSurf]. | ||
[ | <div style="clear:both"></div> | ||
[[ | __TOC__ | ||
[ | </StructureSection> | ||
[[Category: Infectious bursal disease virus]] | [[Category: Infectious bursal disease virus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Abaitua F]] | ||
[[Category: | [[Category: Garriga D]] | ||
[[Category: | [[Category: Navarro A]] | ||
[[Category: Querol-Audi J]] | |||
[[Category: Rodriguez JF]] | |||
[[Category: Verdaguer N]] | |||
Latest revision as of 09:20, 21 February 2024
Crystal structure of infectious bursal disease virus VP1 polymerase, cocrystallized with an oligopeptide mimicking the VP3 C-terminus.
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