2px7: Difference between revisions
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==Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8== | |||
<StructureSection load='2px7' size='340' side='right'caption='[[2px7]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2px7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PX7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2px7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2px7 OCA], [https://pdbe.org/2px7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2px7 RCSB], [https://www.ebi.ac.uk/pdbsum/2px7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2px7 ProSAT], [https://www.topsan.org/Proteins/RSGI/2px7 TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ISPD_THET8 ISPD_THET8] Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity). | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/px/2px7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2px7 ConSurf]. | |||
<div style="clear:both"></div> | |||
== | ==See Also== | ||
*[[MEP cytidylyltransferase 3D structures|MEP cytidylyltransferase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Large Structures]] | ||
[[Category: | [[Category: Thermus thermophilus HB8]] | ||
[[Category: Thermus thermophilus | [[Category: Chang S-H]] | ||
[[Category: Chang | [[Category: Chen L]] | ||
[[Category: Chen | [[Category: Chen L-Q]] | ||
[[Category: Chen | [[Category: Ebihara A]] | ||
[[Category: Ebihara | [[Category: Kuramitsu S]] | ||
[[Category: Kuramitsu | [[Category: Lee D]] | ||
[[Category: Lee | [[Category: Liu Z-J]] | ||
[[Category: Liu | [[Category: Nguyen D]] | ||
[[Category: Nguyen | [[Category: Rose JP]] | ||
[[Category: Shinkai A]] | |||
[[Category: Rose | [[Category: Tsukuda M]] | ||
[[Category: Wang B-C]] | |||
[[Category: Shinkai | [[Category: Yokoyama S]] | ||
[[Category: Tsukuda | |||
[[Category: Wang | |||
[[Category: Yokoyama | |||
Latest revision as of 11:11, 30 August 2023
Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from Thermus thermophilus HB8
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