1yis: Difference between revisions
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== | ==Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase== | ||
<StructureSection load='1yis' size='340' side='right'caption='[[1yis]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
[[ | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1yis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yis OCA], [https://pdbe.org/1yis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yis RCSB], [https://www.ebi.ac.uk/pdbsum/1yis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yis ProSAT], [https://www.topsan.org/Proteins/SECSG/1yis TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PUR8_CAEEL PUR8_CAEEL] Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yis_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1yis ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Adenylosuccinate lyase 3D structures|Adenylosuccinate lyase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: An | [[Category: An J]] | ||
[[Category: Arabshahi | [[Category: Arabshahi A]] | ||
[[Category: Bray | [[Category: Bray T]] | ||
[[Category: Cao | [[Category: Cao Z]] | ||
[[Category: Chen | [[Category: Chen Y-J]] | ||
[[Category: Delucas | [[Category: Delucas L]] | ||
[[Category: Gray | [[Category: Gray R]] | ||
[[Category: Huang | [[Category: Huang W]] | ||
[[Category: Johnson | [[Category: Johnson D]] | ||
[[Category: Karpova | [[Category: Karpova E]] | ||
[[Category: Li | [[Category: Li S]] | ||
[[Category: Lu | [[Category: Lu S]] | ||
[[Category: Luan | [[Category: Luan C-H]] | ||
[[Category: Luo | [[Category: Luo D]] | ||
[[Category: Luo | [[Category: Luo M]] | ||
[[Category: McKinstry | [[Category: McKinstry A]] | ||
[[Category: Qiu | [[Category: Qiu S]] | ||
[[Category: Schormann N]] | |||
[[Category: Schormann | [[Category: Shang Q]] | ||
[[Category: Shang | [[Category: Symersky J]] | ||
[[Category: Symersky | [[Category: Tsao J]] | ||
[[Category: Tsao | [[Category: Zhang Y]] | ||
[[Category: Zhang | [[Category: Zhou J]] | ||
[[Category: Zhou | |||
Latest revision as of 07:31, 9 October 2024
Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
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