3w4k: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 3w4k is ~~ON HOLD~~

==Crystal Structure of human DAAO in complex with coumpound 13==

== Structural highlights ==

<table><tr><td colspan='2'>[[3w4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4K OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=3W4K FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3LD:3-HYDROXY-6-(2-PHENYLETHYL)PYRIDAZIN-4(1H)-ONE'>3LD</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=3w4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4k OCA], [https://pdbe.org/3w4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4k RCSB], [https://www.ebi.ac.uk/pdbsum/3w4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4k ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref>

~~Authors~~: ~~Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K,~~ Hamajima, T, Harada, K~~, Sakashita, H,~~ Matsumoto, Y, Orita, M~~, Watanabe, T,~~ Takeuchi, M

==See Also==

*[[Amino acid oxidase 3D structures|Amino acid oxidase 3D structures]]

~~Description~~: ~~Crystal Structure of human DAAO in complex with coumpound 13~~

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Hamajima T]]

[[Category: Harada K]]

[[Category: Hondo T]]

[[Category: Matsumoto Y]]

[[Category: Nakanishi K]]

[[Category: Namatame I]]

[[Category: Niimi T]]

[[Category: Orita M]]

[[Category: Sakashita H]]

[[Category: Takeuchi M]]

[[Category: Warizaya M]]

[[Category: Watanabe T]]

[[Category: Yamaguchi T]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 3w4k is ON HOLD
+==Crystal Structure of human DAAO in complex with coumpound 13==
+<StructureSection load='3w4k' size='340' side='right'caption='[[3w4k]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[3w4k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W4K FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3LD:3-HYDROXY-6-(2-PHENYLETHYL)PYRIDAZIN-4(1H)-ONE'>3LD</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4k OCA], [https://pdbe.org/3w4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4k RCSB], [https://www.ebi.ac.uk/pdbsum/3w4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4k ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref>
-Authors: Hondo, T, Warizaya, M, Niimi, T, Namatame, I, Yamaguchi, T, Nakanishi, K, Hamajima, T, Harada, K, Sakashita, H, Matsumoto, Y, Orita, M, Watanabe, T, Takeuchi, M
+==See Also==
+*[[Amino acid oxidase 3D structures|Amino acid oxidase 3D structures]]
-Description: Crystal Structure of human DAAO in complex with coumpound 13
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Hamajima T]]
+[[Category: Harada K]]
+[[Category: Hondo T]]
+[[Category: Matsumoto Y]]
+[[Category: Nakanishi K]]
+[[Category: Namatame I]]
+[[Category: Niimi T]]
+[[Category: Orita M]]
+[[Category: Sakashita H]]
+[[Category: Takeuchi M]]
+[[Category: Warizaya M]]
+[[Category: Watanabe T]]
+[[Category: Yamaguchi T]]