1yo7: Difference between revisions

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[[Image:1yo7.gif|left|200px]]<br /><applet load="1yo7" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1yo7, resolution 2.8&Aring;" />
'''Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle'''<br />


==About this Structure==
==Re-engineering topology of the homodimeric ROP protein into a single-chain 4-helix bundle==
1YO7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA].  
<StructureSection load='1yo7' size='340' side='right'caption='[[1yo7]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1yo7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YO7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YO7 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yo7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yo7 OCA], [https://pdbe.org/1yo7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yo7 RCSB], [https://www.ebi.ac.uk/pdbsum/1yo7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yo7 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ROP_ECOLX ROP_ECOLX] Regulates plasmid DNA replication by modulating the initiation of transcription of the primer RNA precursor. Processing of the precursor of the primer, RNAII, is inhibited by hydrogen bonding of RNAII to its complementary sequence in RNAI. ROP increases the affinity of RNAI for RNAII and thus decreases the rate of replication initiation events.
 
==See Also==
*[[Rop protein|Rop protein]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Emery, S C.]]
[[Category: Emery SC]]
[[Category: Sagermann, M.]]
[[Category: Sagermann M]]
[[Category: Sander, C.]]
[[Category: Sander C]]
[[Category: ZN]]
[[Category: four-helix bundle]]
[[Category: protein design]]
[[Category: re-engineering of topology]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:07:25 2008''