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[[Image:4dwg.jpg|left|200px]]


{{STRUCTURE_4dwg| PDB=4dwg | SCENE= }}
==Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+==
<StructureSection load='4dwg' size='340' side='right'caption='[[4dwg]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dwg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DWG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0M8:[2-(HEPTYLAMINO)ETHANE-1,1-DIYL]BIS(PHOSPHONIC+ACID)'>0M8</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dwg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dwg OCA], [https://pdbe.org/4dwg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dwg RCSB], [https://www.ebi.ac.uk/pdbsum/4dwg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dwg ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q95WL3_TRYCR Q95WL3_TRYCR]


===Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+===
==See Also==
 
*[[Farnesyl diphosphate synthase 3D structures|Farnesyl diphosphate synthase 3D structures]]
{{ABSTRACT_PUBMED_22715997}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[4dwg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DWG OCA].
[[Category: Geranyltranstransferase]]
[[Category: Trypanosoma cruzi]]
[[Category: Trypanosoma cruzi]]
[[Category: Amzel, L M.]]
[[Category: Amzel LM]]
[[Category: Aripirala, S.]]
[[Category: Aripirala S]]
[[Category: Gabelli, S B.]]
[[Category: Gabelli SB]]
[[Category: Geranyl transferase]]
[[Category: Transferase-transferase inhibitor complex]]

Latest revision as of 14:46, 14 March 2024

Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+

4dwg, resolution 2.01Å

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