2m2b: Difference between revisions
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==NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens== | |||
<StructureSection load='2m2b' size='340' side='right'caption='[[2m2b]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2m2b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M2B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M2B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m2b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m2b OCA], [https://pdbe.org/2m2b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m2b RCSB], [https://www.ebi.ac.uk/pdbsum/2m2b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m2b ProSAT]</span></td></tr> | ||
[[2m2b]] is a 1 chain structure with sequence from [ | </table> | ||
== Disease == | |||
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] TARP syndrome. TARP syndrome (TARPS) [MIM:[https://omim.org/entry/311900 311900]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Dutta SK]] | ||
[[Category: | [[Category: Fox BG]] | ||
[[Category: | [[Category: Geralt M]] | ||
[[Category: Makino S]] | |||
[[Category: Makino | [[Category: Markley JL]] | ||
[[Category: Markley | [[Category: Misenhiemer TM]] | ||
[[Category: Misenhiemer | [[Category: Serrano P]] | ||
[[Category: Serrano | [[Category: Wrobel RL]] | ||
[[Category: Wuthrich K]] | |||
[[Category: Wrobel | |||
[[Category: Wuthrich | |||
Latest revision as of 05:58, 15 May 2024
NMR structure of the RRM2 domain of the protein RBM10 from Homo sapiens
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