3v7k: Difference between revisions

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[[Image:3v7k.jpg|left|200px]]


{{STRUCTURE_3v7k| PDB=3v7k | SCENE= }}
==Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex==
<StructureSection load='3v7k' size='340' side='right'caption='[[3v7k]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3v7k]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V7K FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.271&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v7k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v7k OCA], [https://pdbe.org/3v7k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v7k RCSB], [https://www.ebi.ac.uk/pdbsum/3v7k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v7k ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPOLB_RAT DPOLB_RAT] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.


===Co-crystal structure of K72E variant of rat polymerase beta: Enzyme-DNA binary complex===
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3v7k]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V7K OCA].
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Jaeger, J.]]
[[Category: Jaeger J]]
[[Category: Rangarajan, S.]]
[[Category: Rangarajan S]]
[[Category: Protein-dna complex]]
[[Category: Repair polymerase]]
[[Category: Transferase-dna complex]]
Retrieved from "https://proteopedia.org/3v7k"