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[[Image:4fnv.png|left|200px]]


{{STRUCTURE_4fnv|  PDB=4fnv  |  SCENE=  }}
==Crystal Structure of Heparinase III==
 
<StructureSection load='4fnv' size='340' side='right'caption='[[4fnv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
===Crystal Structure of Heparinase III===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4fnv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FNV FirstGlance]. <br>
{{ABSTRACT_PUBMED_23011846}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fnv OCA], [https://pdbe.org/4fnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fnv RCSB], [https://www.ebi.ac.uk/pdbsum/4fnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fnv ProSAT]</span></td></tr>
==About this Structure==
</table>
[[4fnv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FNV OCA].  
== Function ==
[[Category: Bacteroides thetaiotaomicron]]
[https://www.uniprot.org/uniprot/HEPC_BACTN HEPC_BACTN] Specifically cleaves heparan sulfate-rich regions of acidic polysaccharides. Does not act on N,O-desulfated glucosamine or N-acetyl-O-sulfated glucosamine linkages. Functions in cleaving metazoan heparan sulfate and providing carbon, nitrogen and sulfate sources for microorganisms.<ref>PMID:23011846</ref>
[[Category: Dong, W.]]
== References ==
[[Category: Ye, S.]]
<references/>
[[Category: -sandwich fold]]
__TOC__
[[Category: Heparan sulfate degradation]]
</StructureSection>
[[Category: Lyase]]
[[Category: Bacteroides thetaiotaomicron VPI-5482]]
[[Category: Toroid fold]]
[[Category: Large Structures]]
[[Category: Dong W]]
[[Category: Ye S]]

Latest revision as of 11:19, 1 March 2024

Crystal Structure of Heparinase III

4fnv, resolution 1.60Å

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