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[[Image:1h0m.png|left|200px]]


{{STRUCTURE_1h0m| PDB=1h0m | SCENE= }}
==Three-dimensional structure of the quorum sensing protein TraR bound to its autoinducer and to its target DNA==
<StructureSection load='1h0m' size='340' side='right'caption='[[1h0m]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1h0m]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0M FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LAE:3-OXO-OCTANOIC+ACID+(2-OXO-TETRAHYDRO-FURAN-3-YL)-AMIDE'>LAE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0m OCA], [https://pdbe.org/1h0m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0m RCSB], [https://www.ebi.ac.uk/pdbsum/1h0m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0m ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRAR_RHIRD TRAR_RHIRD] Positive regulation of conjugal transfer of Ti plasmids. TraR activates target genes in the presence of AAI and also activates traR and traI themselves.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/1h0m_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h0m ConSurf].
<div style="clear:both"></div>


===THREE-DIMENSIONAL STRUCTURE OF THE QUORUM SENSING PROTEIN TRAR BOUND TO ITS AUTOINDUCER AND TO ITS TARGET DNA===
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
{{ABSTRACT_PUBMED_12198141}}
__TOC__
 
</StructureSection>
==About this Structure==
[[1h0m]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Agrobacterium_tumefaciens Agrobacterium tumefaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0M OCA].
 
==Reference==
<ref group="xtra">PMID:012198141</ref><references group="xtra"/>
[[Category: Agrobacterium tumefaciens]]
[[Category: Agrobacterium tumefaciens]]
[[Category: Cortese, R.]]
[[Category: Large Structures]]
[[Category: Francesco, R De.]]
[[Category: Synthetic construct]]
[[Category: Gargioli, C.]]
[[Category: Cortese R]]
[[Category: Marco, S Di.]]
[[Category: De Francesco R]]
[[Category: Muraglia, E.]]
[[Category: Di Marco S]]
[[Category: Neddermann, P.]]
[[Category: Gargioli C]]
[[Category: Vannini, A.]]
[[Category: Muraglia E]]
[[Category: Volpari, C.]]
[[Category: Neddermann P]]
[[Category: Dna-binding protein]]
[[Category: Vannini A]]
[[Category: Homoserine lactone]]
[[Category: Volpari C]]
[[Category: Luxr-type protein]]
[[Category: Quorum sensing]]
[[Category: Transcription-dna complex]]
[[Category: Transcription/dna]]
[[Category: Transcriptional regulator]]
[[Category: Trar]]