3w4y: Difference between revisions
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New page: '''Unreleased structure''' The entry 3w4y is ON HOLD Authors: Shin, K, Kayoko, T, Nobuhisa, W, Toshiya, E Description: Crystal structure of yeast Erv1 core |
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==Crystal structure of yeast Erv1 core== | |||
<StructureSection load='3w4y' size='340' side='right'caption='[[3w4y]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3w4y]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W4Y FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w4y OCA], [https://pdbe.org/3w4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w4y RCSB], [https://www.ebi.ac.uk/pdbsum/3w4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w4y ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ERV1_YEAST ERV1_YEAST] FAD-dependent sulfhydryl oxidase that catalyzes disulfide bond formation. Required for the import and folding of small cysteine-containing proteins in the mitochondrial intermembrane space (IMS). Forms a redox cycle with MIA40 that involves a disulfide relay system. Important for maintaining the cysteine residues in MIA40 in an oxidized state. Reduced ERV1 is reoxidized by cytochrome c. Required for the maturation of cytoplasmic, but not of mitochondrial Fe/S proteins.[PROSITE-ProRule:PRU00654]<ref>PMID:10899311</ref> <ref>PMID:11493598</ref> <ref>PMID:12654008</ref> <ref>PMID:15989955</ref> <ref>PMID:16181637</ref> <ref>PMID:16185707</ref> | |||
==See Also== | |||
*[[Sulfhydryl oxidase 3D structures|Sulfhydryl oxidase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae S288C]] | |||
[[Category: Endo T]] | |||
[[Category: Kawano S]] | |||
[[Category: Terao K]] | |||
[[Category: Watanabe N]] | |||
Latest revision as of 12:49, 8 November 2023
Crystal structure of yeast Erv1 core
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