4itd: Difference between revisions
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New page: '''Unreleased structure''' The entry 4itd is ON HOLD Authors: Zhang, F., Suzuki, K., Tsunoda, M., Wilkinson, O., Millington, C.L., Williams, D.M., Morishita, E.C., Takenaka, A. Descrip... |
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==Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation== | |||
<StructureSection load='4itd' size='340' side='right'caption='[[4itd]], [[Resolution|resolution]] 1.94Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4itd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ITD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ITD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C6G:6-(CARBOXYMETHOXY)-9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-9H-PURIN-2-AMINE'>C6G</scene>, <scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4itd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4itd OCA], [https://pdbe.org/4itd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4itd RCSB], [https://www.ebi.ac.uk/pdbsum/4itd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4itd ProSAT]</span></td></tr> | |||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Millington CL]] | |||
[[Category: Morishita EC]] | |||
[[Category: Suzuki K]] | |||
[[Category: Takenaka A]] | |||
[[Category: Tsunoda M]] | |||
[[Category: Wilkinson O]] | |||
[[Category: Williams DM]] | |||
[[Category: Zhang F]] | |||
Latest revision as of 08:53, 20 March 2024
Structures of DNA duplexes containing O6-carboxymethylguanine, a lesion associated with gastrointestinal cancer, reveal a mechanism for inducing transition mutation
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