4ixd: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "4ixd" [edit=sysop:move=sysop] |
No edit summary |
||
| (7 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==X-ray structure of lfa-1 i-domain in complex with ibe-667 at 1.8a resolution== | |||
<StructureSection load='4ixd' size='340' side='right'caption='[[4ixd]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ixd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IXD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4IXD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1HV:4-(3-{4-[(3-AMINOPROPYL)CARBAMOYL]PHENYL}-1H-INDAZOL-1-YL)-N-METHYLBENZAMIDE'>1HV</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ixd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ixd OCA], [https://pdbe.org/4ixd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ixd RCSB], [https://www.ebi.ac.uk/pdbsum/4ixd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ixd ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ITAL_HUMAN ITAL_HUMAN] Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. | |||
==See Also== | |||
*[[Integrin 3D structures|Integrin 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Kallen J]] | |||