4iy3: Difference between revisions
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==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | |||
<StructureSection load='4iy3' size='340' side='right' caption='[[4iy3]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4iy3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY3 FirstGlance]. <br> | |||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy0|4iy0]], [[4iy2|4iy2]], [[4iy4|4iy4]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy3 OCA], [http://pdbe.org/4iy3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4iy3 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4iy3 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CNNM4_HUMAN CNNM4_HUMAN]] Jalili syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CNNM4_HUMAN CNNM4_HUMAN]] Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions (By similarity). May play a role in biomineralization and retinal function.<ref>PMID:19200527</ref> <ref>PMID:19200525</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Human]] | |||
[[Category: Accardi, A]] | |||
[[Category: Corral-Rodriguez, M A]] | |||
[[Category: Diercks, T]] | |||
[[Category: Encinar, J A]] | |||
[[Category: Ereno-Orbea, J]] | |||
[[Category: Gomez-Garcia, I]] | |||
[[Category: Martinez-Cruz, L A]] | |||
[[Category: Muller, D]] | |||
[[Category: Oyenarte, I]] | |||
[[Category: Spiwok, V]] | |||
[[Category: Stuiver, M]] | |||
[[Category: Terashima, H]] | |||
[[Category: Cbs domain]] | |||
[[Category: Cytosol]] | |||
[[Category: Magnesium transport]] | |||
[[Category: Metal transport]] | |||
Latest revision as of 14:21, 11 August 2016
Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4
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