3aqc: Difference between revisions
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==M. luteus B-P 26 heterodimeric hexaprenyl diphosphate synthase in complex with magnesium and FPP analogue== | |||
<StructureSection load='3aqc' size='340' side='right'caption='[[3aqc]], [[Resolution|resolution]] 2.61Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3aqc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Micrococcus_luteus Micrococcus luteus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AQC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AQC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2DE:(2E,6E)-7,11-DIMETHYLDODECA-2,6,10-TRIEN-1-YL+TRIHYDROGEN+DIPHOSPHATE'>2DE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aqc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aqc OCA], [https://pdbe.org/3aqc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aqc RCSB], [https://www.ebi.ac.uk/pdbsum/3aqc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aqc ProSAT]</span></td></tr> | ||
[[3aqc]] is a 4 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/HEXA_MICLU HEXA_MICLU] Catalyzes the condensation of three molecules of isopentenyl diphosphate with farnesyl diphosphate (FPP) to yield (all-E)-hexaprenyl diphosphate (HexPP; C30), the precursor of the prenyl side chain of menaquinone-6. Large subunit Hexs-B catalyzes the condensation reaction and the final product chain length is cooperatively regulated by both the Hexs-A and Hexs-B subunits using the whole size of the hydrophobic cleft as a ruler.<ref>PMID:11514159</ref> <ref>PMID:7174655</ref> <ref>PMID:9515931</ref> | ||
< | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Micrococcus luteus]] | [[Category: Micrococcus luteus]] | ||
[[Category: Fujihashi M]] | |||
[[Category: Fujihashi | [[Category: Kobayashi Y]] | ||
[[Category: Kobayashi | [[Category: Koyama T]] | ||
[[Category: Koyama | [[Category: Miki K]] | ||
[[Category: Miki | [[Category: Noike M]] | ||
[[Category: Noike | [[Category: Okuyama N]] | ||
[[Category: Okuyama | [[Category: Sasaki D]] | ||
[[Category: Sasaki | |||
Latest revision as of 14:01, 13 March 2024
M. luteus B-P 26 heterodimeric hexaprenyl diphosphate synthase in complex with magnesium and FPP analogue
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