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[[Image:4gcs.png|left|200px]]


{{STRUCTURE_4gcs|  PDB=4gcs  |  SCENE=  }}
==Crystal Structure of E. coli OmpF porin in complex with Ertapenem==
 
<StructureSection load='4gcs' size='340' side='right'caption='[[4gcs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
===Crystal Structure of E. coli OmpF porin in complex with Ertapenem===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4gcs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GCS FirstGlance]. <br>
{{ABSTRACT_PUBMED_23201272}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1RG:(4R,5S)-3-({(3S,5S)-5-[(3-CARBOXYPHENYL)CARBAMOYL]PYRROLIDIN-3-YL}SULFANYL)-5-[(1S,2R)-1-FORMYL-2-HYDROXYPROPYL]-4-METHYL-4,5-DIHYDRO-1H-PYRROLE-2-CARBOXYLIC+ACID'>1RG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gcs OCA], [https://pdbe.org/4gcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gcs RCSB], [https://www.ebi.ac.uk/pdbsum/4gcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gcs ProSAT]</span></td></tr>
[[4gcs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCS OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/OMPF_ECOLI OMPF_ECOLI] Forms pores that allow passive diffusion of small molecules across the outer membrane. It is also a receptor for the bacteriophage T2.<ref>PMID:19721064</ref>


==See Also==
==See Also==
*[[Porin|Porin]]
*[[Porin 3D structures|Porin 3D structures]]
[[Category: Escherichia coli k-12]]
== References ==
[[Category: Roux, B.]]
<references/>
[[Category: Ziervogel, B K.]]
__TOC__
[[Category: Beta-barrel]]
</StructureSection>
[[Category: Ertapenem binding]]
[[Category: Escherichia coli K-12]]
[[Category: Membrane protein-antibiotic complex]]
[[Category: Large Structures]]
[[Category: Non-specific channel]]
[[Category: Roux B]]
[[Category: Outer membrane]]
[[Category: Ziervogel BK]]
[[Category: Protein-drug complex]]
[[Category: Trimer]]