4j4a: Difference between revisions
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==Crystal Structure of Engineered Trimeric Cortexillin-1 Coiled-Coil Variant== | |||
<StructureSection load='4j4a' size='340' side='right'caption='[[4j4a]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4j4a]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4J4A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4J4A FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6499Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4j4a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4j4a OCA], [https://pdbe.org/4j4a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4j4a RCSB], [https://www.ebi.ac.uk/pdbsum/4j4a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4j4a ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CTXA_DICDI CTXA_DICDI] Acting-bundling protein. When linked to F-actin the actin filaments form preferentially anti-parallel bundles that associate into meshworks. Plays a major role in cytokinesis. Negatively regulates cortical localization of rapgap1.<ref>PMID:18039932</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Dictyostelium discoideum]] | |||
[[Category: Large Structures]] | |||
[[Category: Bjelic S]] | |||
[[Category: Kammerer RA]] | |||
[[Category: Steinmetz MO]] | |||
Latest revision as of 12:01, 1 March 2024
Crystal Structure of Engineered Trimeric Cortexillin-1 Coiled-Coil Variant
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