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[[Image:211d.gif|left|200px]]<br /><applet load="211d" size="350" color="white" frame="true" align="right" spinBox="true"
caption="211d, resolution 1.600&Aring;" />
'''THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE'''<br />


==Overview==
==THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE==
<StructureSection load='211d' size='340' side='right'caption='[[211d]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[211d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=211D FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=PTN:PLATINUM+TRIAMINE+ION'>PTN</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=211d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=211d OCA], [https://pdbe.org/211d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=211d RCSB], [https://www.ebi.ac.uk/pdbsum/211d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=211d ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.
The three-dimensional structure of d[CGTA'CG], where A' = [2-NH2-A], was determined to atomic (1.35 A) resolution by single isomorphous replacement. The d[CGTA'CG] hexamer crystallizes in space group P3221, and is not isomorphous with other DNA hexanucleotides. Despite completely different crystal packing, the essential characteristics of the Z-DNA conformation are maintained. The structure was determined by single isomorphous replacement using a triammine platinum fragment. Thus, this study also demonstrates, for the first time, the feasibility of the use of this reagent for the direct phasing of DNA crystal structures.


==About this Structure==
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative.,Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:7492550<ref>PMID:7492550</ref>
211D is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=PTN:'>PTN</scene> and <scene name='pdbligand=SPM:'>SPM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=211D OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
Crystal and molecular structure of a new Z-DNA crystal form: d[CGT(2-NH2-A)CG] and its platinated derivative., Parkinson GN, Arvanitis GM, Lessinger L, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1995 Nov 28;34(47):15487-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7492550 7492550]
</div>
[[Category: Protein complex]]
<div class="pdbe-citations 211d" style="background-color:#fffaf0;"></div>
[[Category: Arvantis, G M.]]
== References ==
[[Category: Berman, H M.]]
<references/>
[[Category: Gaffney, B.]]
__TOC__
[[Category: Ginell, S L.]]
</StructureSection>
[[Category: Jones, R.]]
[[Category: Large Structures]]
[[Category: Lessinger, L.]]
[[Category: Arvantis GM]]
[[Category: Parkinson, G N.]]
[[Category: Berman HM]]
[[Category: PTN]]
[[Category: Gaffney B]]
[[Category: SPM]]
[[Category: Ginell SL]]
[[Category: double helix]]
[[Category: Jones R]]
[[Category: modified]]
[[Category: Lessinger L]]
[[Category: z-dna]]
[[Category: Parkinson GN]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:20:58 2008''

Latest revision as of 07:41, 13 August 2026

THE CRYSTAL AND MOLECULAR STRUCTURE OF A NEW Z-DNA CRYSTAL FORM: D[CGT(2-NH2-A) CG] AND ITS PLATINATED DERIVATIVE

211d, resolution 1.60Å

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