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[[Image:4dof.jpg|left|200px]]


{{STRUCTURE_4dof| PDB=4dof | SCENE= }}
==Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms==
<StructureSection load='4dof' size='340' side='right'caption='[[4dof]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4dof]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Western_Reserve Vaccinia virus Western Reserve]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DOF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dof OCA], [https://pdbe.org/4dof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dof RCSB], [https://www.ebi.ac.uk/pdbsum/4dof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dof ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/UNG_VACCW UNG_VACCW] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity).


===Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms===
==See Also==
 
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4dof]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus_ankara Vaccinia virus ankara]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DOF OCA].
[[Category: Large Structures]]
[[Category: Uracil-DNA glycosylase]]
[[Category: Vaccinia virus Western Reserve]]
[[Category: Vaccinia virus ankara]]
[[Category: Chattopadhyay D]]
[[Category: Chattopadhyay, D.]]
[[Category: Schormann N]]
[[Category: Schormann, N.]]
[[Category: Dna binding component]]
[[Category: Dna repair]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Viral processivity factor]]

Latest revision as of 14:40, 14 March 2024

Structures of Vaccinia Virus Uracil-DNA Glycosylase in New Crystal Forms

4dof, resolution 2.80Å

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