3fr1: Difference between revisions

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[[Image:3fr1.png|left|200px]]


{{STRUCTURE_3fr1|  PDB=3fr1  |  SCENE=  }}
==NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)==
 
<StructureSection load='3fr1' size='340' side='right'caption='[[3fr1]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
===NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3fr1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FR1 FirstGlance]. <br>
{{ABSTRACT_PUBMED_19684598}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fr1 OCA], [https://pdbe.org/3fr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fr1 RCSB], [https://www.ebi.ac.uk/pdbsum/3fr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fr1 ProSAT]</span></td></tr>
[[3fr1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FR1 OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
<ref group="xtra">PMID:019684598</ref><references group="xtra"/>
__TOC__
[[Category: Eisenberg, D.]]
</StructureSection>
[[Category: Sawaya, M R.]]
[[Category: Homo sapiens]]
[[Category: Wiltzius, J J.W.]]
[[Category: Large Structures]]
[[Category: Amidation]]
[[Category: Eisenberg D]]
[[Category: Amyloid]]
[[Category: Sawaya MR]]
[[Category: Amyloid-like protofibril]]
[[Category: Wiltzius JJW]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Hormone]]
[[Category: Protein fibril]]
[[Category: Secreted]]

Latest revision as of 09:50, 21 February 2024

NFLVHS segment from Islet Amyloid Polypeptide (IAPP or Amylin)

3fr1, resolution 1.85Å

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