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[[Image:3g06.png|left|200px]]


{{STRUCTURE_3g06|  PDB=3g06  |  SCENE=  }}
==The Salmonella Virulence Effector SspH2 Functions As A Novel E3 Ligase==
 
<StructureSection load='3g06' size='340' side='right'caption='[[3g06]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
===The Salmonella Virulence Effector SspH2 Functions As A Novel E3 Ligase===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3g06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G06 FirstGlance]. <br>
{{ABSTRACT_PUBMED_19273841}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g06 OCA], [https://pdbe.org/3g06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g06 RCSB], [https://www.ebi.ac.uk/pdbsum/3g06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g06 ProSAT]</span></td></tr>
==About this Structure==
</table>
[[3g06]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G06 OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/SSPH2_SALTY SSPH2_SALTY] Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway.
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:019273841</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
Check<jmol>
[[Category: Ubiquitin--protein ligase]]
  <jmolCheckbox>
[[Category: Quezada, C M.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g0/3g06_consurf.spt"</scriptWhenChecked>
[[Category: Stebbins, C E.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: E3 ubiquitin ligase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Leucine rich repeat domain]]
  </jmolCheckbox>
[[Category: Ligase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g06 ConSurf].
[[Category: Salmonella virulence factor]]
<div style="clear:both"></div>
[[Category: Spi-2]]
__TOC__
[[Category: Type three effector]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Quezada CM]]
[[Category: Stebbins CE]]
Retrieved from "https://proteopedia.org/3g06"