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[[Image:3gri.png|left|200px]]


{{STRUCTURE_3gri|  PDB=3gri  |  SCENE=  }}
==The Crystal Structure of a Dihydroorotase from Staphylococcus aureus==
 
<StructureSection load='3gri' size='340' side='right'caption='[[3gri]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===The Crystal Structure of a Dihydroorotase from Staphylococcus aureus===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3gri]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staaw Staaw]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GRI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GRI FirstGlance]. <br>
 
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
==About this Structure==
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[3gri]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mw2 Staphylococcus aureus subsp. aureus mw2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GRI OCA].  
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MW1084, pyrC, pyrC SACOL1213 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=196620 STAAW])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydroorotase Dihydroorotase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.3 3.5.2.3] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3gri FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3gri OCA], [https://pdbe.org/3gri PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3gri RCSB], [https://www.ebi.ac.uk/pdbsum/3gri PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3gri ProSAT], [https://www.topsan.org/Proteins/CSGID/3gri TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/3gri_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3gri ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Dihydroorotase]]
[[Category: Dihydroorotase]]
[[Category: Staphylococcus aureus subsp. aureus mw2]]
[[Category: Large Structures]]
[[Category: Anderson, W F.]]
[[Category: Staaw]]
[[Category: Brunzelle, J S.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Brunzelle, J S]]
[[Category: Onopriyenko, O.]]
[[Category: Structural genomic]]
[[Category: Savchenko, A.]]
[[Category: Onopriyenko, O]]
[[Category: Skarina, T.]]
[[Category: Savchenko, A]]
[[Category: Wawrzak, Z.]]
[[Category: Skarina, T]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Wawrzak, Z]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
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[[Category: Metal-binding]]
[[Category: Metal-binding]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Structural genomic]]

Latest revision as of 07:53, 16 March 2022

The Crystal Structure of a Dihydroorotase from Staphylococcus aureus

3gri, resolution 2.00Å

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