2ap9: Difference between revisions

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[[Image:2ap9.gif|left|200px]]<br /><applet load="2ap9" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2ap9, resolution 2.80&Aring;" />
'''Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551'''<br />


==About this Structure==
==Crystal structure of acetylglutamate kinase from Mycobacterium tuberculosis CDC1551==
2AP9 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_cdc1551 Mycobacterium tuberculosis cdc1551] with <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=NI:'>NI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AP9 OCA].  
<StructureSection load='2ap9' size='340' side='right'caption='[[2ap9]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
[[Category: Acetylglutamate kinase]]
== Structural highlights ==
[[Category: Mycobacterium tuberculosis cdc1551]]
<table><tr><td colspan='2'>[[2ap9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_CDC1551 Mycobacterium tuberculosis CDC1551]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AP9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AP9 FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Burley, S K.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
[[Category: Kniewel, R.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ap9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ap9 OCA], [https://pdbe.org/2ap9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ap9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ap9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ap9 ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2ap9 TOPSAN]</span></td></tr>
[[Category: Lee, K.]]
</table>
[[Category: Lima, C D.]]
== Function ==
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[https://www.uniprot.org/uniprot/ARGB_MYCTU ARGB_MYCTU]  
[[Category: Rajashankar, K R.]]
== Evolutionary Conservation ==
[[Category: MG]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: NI]]
Check<jmol>
[[Category: structural genomics; protein structure initiative; nysgxrc; t1702; acetylglutamate kinase; psi; new york structural genomix research consortium]]
  <jmolCheckbox>
 
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ap/2ap9_consurf.spt"</scriptWhenChecked>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:29:31 2008''
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ap9 ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis CDC1551]]
[[Category: Burley SK]]
[[Category: Kniewel R]]
[[Category: Lee K]]
[[Category: Lima CD]]
[[Category: Rajashankar KR]]