3h90: Difference between revisions
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==Structural basis for the autoregulation of the zinc transporter YiiP== | |||
<StructureSection load='3h90' size='340' side='right'caption='[[3h90]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3h90]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H90 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h90 OCA], [https://pdbe.org/3h90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h90 RCSB], [https://www.ebi.ac.uk/pdbsum/3h90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h90 ProSAT]</span></td></tr> | ||
[[3h90]] is a 4 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/FIEF_ECOLI FIEF_ECOLI] Iron-efflux transporter responsible for iron detoxification. Also able to transport Zn(2+) in a proton-dependent manner.<ref>PMID:15549269</ref> | ||
< | == Evolutionary Conservation == | ||
[[ | [[Image:Consurf_key_small.gif|200px|right]] | ||
[ | Check<jmol> | ||
[ | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h9/3h90_consurf.spt"</scriptWhenChecked> | |||
[ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
[[ | <text>to colour the structure by Evolutionary Conservation</text> | ||
[ | </jmolCheckbox> | ||
[[ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h90 ConSurf]. | ||
[ | <div style="clear:both"></div> | ||
== References == | |||
[[Category: | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Lu M]] | |||
Latest revision as of 09:58, 21 February 2024
Structural basis for the autoregulation of the zinc transporter YiiP
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