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[[Image:3hd2.png|left|200px]]


{{STRUCTURE_3hd2| PDB=3hd2 | SCENE= }}
==Crystal structure of E. coli HPPK(Q50A) in complex with MgAMPCPP and pterin==
<StructureSection load='3hd2' size='340' side='right'caption='[[3hd2]], [[Resolution|resolution]] 1.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3hd2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HD2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PE0:PTERINE'>PE0</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hd2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hd2 OCA], [https://pdbe.org/3hd2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hd2 RCSB], [https://www.ebi.ac.uk/pdbsum/3hd2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hd2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HPPK_ECOLI HPPK_ECOLI]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hd/3hd2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hd2 ConSurf].
<div style="clear:both"></div>


===Crystal structure of E. coli HPPK(Q50A) in complex with MgAMPCPP and pterin===
==See Also==
 
*[[HPPK 3D structures|HPPK 3D structures]]
{{ABSTRACT_PUBMED_11546767}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Escherichia coli K-12]]
[[3hd2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HD2 OCA].
[[Category: Large Structures]]
 
[[Category: Blaszczyk J]]
==Reference==
[[Category: Ji X]]
<ref group="xtra">PMID:011546767</ref><references group="xtra"/>
[[Category: Li Y]]
[[Category: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase]]
[[Category: Yan H]]
[[Category: Escherichia coli k-12]]
[[Category: Blaszczyk, J.]]
[[Category: Ji, X.]]
[[Category: Li, Y.]]
[[Category: Yan, H.]]
[[Category: Alpha beta]]
[[Category: Atp-binding]]
[[Category: Folate biosynthesis]]
[[Category: Kinase]]
[[Category: Nucleotide-binding]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/3hd2"