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[[Image:3hfx.png|left|200px]]


{{STRUCTURE_3hfx|  PDB=3hfx  |  SCENE=  }}
==Crystal structure of carnitine transporter==
 
<StructureSection load='3hfx' size='340' side='right'caption='[[3hfx]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
===Crystal structure of carnitine transporter===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3hfx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HFX FirstGlance]. <br>
{{ABSTRACT_PUBMED_20357772}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=152:CARNITINE'>152</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hfx OCA], [https://pdbe.org/3hfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hfx RCSB], [https://www.ebi.ac.uk/pdbsum/3hfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hfx ProSAT]</span></td></tr>
[[3hfx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HFX OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/CAIT_ECOLI CAIT_ECOLI] Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines.
<ref group="xtra">PMID:020357772</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Category: Escherichia coli]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Bai, L.]]
Check<jmol>
[[Category: Jiang, T.]]
  <jmolCheckbox>
[[Category: Tang, L.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hf/3hfx_consurf.spt"</scriptWhenChecked>
[[Category: Wang, W H.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Antiport]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Cell inner membrane]]
  </jmolCheckbox>
[[Category: Cell membrane]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hfx ConSurf].
[[Category: Helix-turn-helix]]
<div style="clear:both"></div>
[[Category: Transmembrane]]
__TOC__
[[Category: Transport]]
</StructureSection>
[[Category: Transport protein]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Bai L]]
[[Category: Jiang T]]
[[Category: Tang L]]
[[Category: Wang W-H]]

Latest revision as of 08:26, 20 March 2024

Crystal structure of carnitine transporter

3hfx, resolution 3.15Å

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