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[[Image:3hit.png|left|200px]]


{{STRUCTURE_3hit|  PDB=3hit  |  SCENE=  }}
==Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue==
 
<StructureSection load='3hit' size='340' side='right'caption='[[3hit]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
===Crystal structure of Saporin-L1 in complex with the dinucleotide inhibitor, a transition state analogue===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3hit]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIT FirstGlance]. <br>
{{ABSTRACT_PUBMED_19920175}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DYN:5-O-[(S)-{[(3R,4R)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-({[(S)-hydroxy(3-hydroxypropoxy)phosphoryl]oxy}methyl)pyrrolidin-3-yl]oxy}(hydroxy)phosphoryl]-3-O-[(R)-hydroxy(4-hydroxybutoxy)phosphoryl]-2-O-methylguanosine'>DYN</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hit OCA], [https://pdbe.org/3hit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hit RCSB], [https://www.ebi.ac.uk/pdbsum/3hit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hit ProSAT]</span></td></tr>
[[3hit]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIT OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/Q2QEH4_SAPOF Q2QEH4_SAPOF]
<ref group="xtra">PMID:019920175</ref><references group="xtra"/>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3hit_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hit ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saponaria officinalis]]
[[Category: Saponaria officinalis]]
[[Category: RRNA N-glycosylase]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Ho M]]
[[Category: Ho, M.]]
[[Category: Schramm VL]]
[[Category: Schramm, V L.]]
[[Category: Sturm MB]]
[[Category: Sturm, M B.]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Plant defense]]
[[Category: Protein synthesis inhibitor]]
[[Category: Ribosome inactivating protein]]
[[Category: Rip]]
[[Category: Toxin]]
[[Category: Transition state]]
Retrieved from "https://proteopedia.org/3hit"