2k2q: Difference between revisions

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{{Large structure}}
{{STRUCTURE_2k2q|  PDB=2k2q  |  SCENE=  }}
===complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain===
{{ABSTRACT_PUBMED_18704089}}


==About this Structure==
==complex structure of the external thioesterase of the Surfactin-synthetase with a carrier domain==
[[2k2q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [http://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2Q OCA].  
<StructureSection load='2k2q' size='340' side='right'caption='[[2k2q]]' scene=''>
 
== Structural highlights ==
==Reference==
<table><tr><td colspan='2'>[[2k2q]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis] and [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K2Q FirstGlance]. <br>
<ref group="xtra">PMID:018704089</ref><references group="xtra"/>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k2q OCA], [https://pdbe.org/2k2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k2q RCSB], [https://www.ebi.ac.uk/pdbsum/2k2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k2q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYCC_BREPA TYCC_BREPA] Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/2k2q_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k2q ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Brevibacillus parabrevis]]
[[Category: Brevibacillus parabrevis]]
[[Category: Bernhard, F.]]
[[Category: Large Structures]]
[[Category: Dotsch, V.]]
[[Category: Bernhard F]]
[[Category: Frueh, D P.]]
[[Category: Dotsch V]]
[[Category: Guntert, P.]]
[[Category: Frueh DP]]
[[Category: Koglin, A.]]
[[Category: Guntert P]]
[[Category: Lohr, F.]]
[[Category: Koglin A]]
[[Category: Marahiel, M A.]]
[[Category: Lohr F]]
[[Category: Mofid, M R.]]
[[Category: Marahiel MA]]
[[Category: Rogov, V R.]]
[[Category: Mofid MR]]
[[Category: Strieter, E R.]]
[[Category: Rogov VV]]
[[Category: Wagner, G.]]
[[Category: Strieter ER]]
[[Category: Walsh, C T.]]
[[Category: Wagner G]]
[[Category: A/b-hydrolase]]
[[Category: Walsh CT]]
[[Category: Antibiotic biosynthesis]]
[[Category: Ligase]]
[[Category: Ligase-hydrolase complex]]
[[Category: Multifunctional enzyme]]
[[Category: Non-ribosomal peptide synthetase]]
[[Category: Nrp]]
[[Category: Phosphopantetheine]]
[[Category: Sporulation]]
[[Category: Stress response]]
[[Category: Thioesterase]]
[[Category: Type ii thioesterase]]
Retrieved from "https://proteopedia.org/2k2q"