2b5u: Difference between revisions

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[[Image:2b5u.gif|left|200px]]<br /><applet load="2b5u" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2b5u, resolution 2.300&Aring;" />
'''Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein'''<br />


==About this Structure==
==Crystal Structure Of Colicin E3 V206C Mutant In Complex With Its Immunity Protein==
2B5U is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5U OCA].  
<StructureSection load='2b5u' size='340' side='right'caption='[[2b5u]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2b5u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B5U FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b5u OCA], [https://pdbe.org/2b5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b5u RCSB], [https://www.ebi.ac.uk/pdbsum/2b5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b5u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CEA3_ECOLX CEA3_ECOLX] Inactivates ribosomes by hydrolyzing 16S RNA in 30S ribosomes at a specific site.  Colicins are polypeptide toxins produced by and active against E.coli and closely related bacteria.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b5/2b5u_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b5u ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Colicin 3D structures|Colicin 3D structures]]
*[[Colicin immunity protein 3D structures|Colicin immunity protein 3D structures]]
__TOC__
</StructureSection>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Protein complex]]
[[Category: Large Structures]]
[[Category: Jakes, K.]]
[[Category: Jakes K]]
[[Category: Nan, W.]]
[[Category: Nallini Vijayarangan A]]
[[Category: Nithianantham, S.]]
[[Category: Nan W]]
[[Category: Shoham, M.]]
[[Category: Nithianantham S]]
[[Category: Vijayarangan, A Nallini.]]
[[Category: Shoham M]]
[[Category: CIT]]
[[Category: colicin e3]]
[[Category: high resolution crystal structure]]
[[Category: immunity protein]]
[[Category: ribosome inactivation]]
 
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Retrieved from "https://proteopedia.org/2b5u"