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{{STRUCTURE_1dks|  PDB=1dks  |  SCENE=  }}
===CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 IN COMPLEX WITH PHOSPHATE===
{{ABSTRACT_PUBMED_7791211}}


==About this Structure==
==CKSHS1: HUMAN CYCLIN DEPENDENT KINASE SUBUNIT, TYPE 1 IN COMPLEX WITH PHOSPHATE==
[[1dks]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKS OCA].  
<StructureSection load='1dks' size='340' side='right'caption='[[1dks]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1dks]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DKS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dks OCA], [https://pdbe.org/1dks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dks RCSB], [https://www.ebi.ac.uk/pdbsum/1dks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dks ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CKS1_HUMAN CKS1_HUMAN] Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dk/1dks_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dks ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Axin|Axin]]
*[[Cyclin-dependent kinase 3D structures|Cyclin-dependent kinase 3D structures]]
 
*[[Cyclin-dependent kinase regulatory subunit|Cyclin-dependent kinase regulatory subunit]]
==Reference==
*[[Cyclin-dependent kinase regulatory subunit 3D structures|Cyclin-dependent kinase regulatory subunit 3D structures]]
<ref group="xtra">PMID:007791211</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arvai, A S.]]
[[Category: Large Structures]]
[[Category: Bourne, Y.]]
[[Category: Arvai AS]]
[[Category: Tainer, J A.]]
[[Category: Bourne Y]]
[[Category: Cell division]]
[[Category: Tainer JA]]
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