2b6p: Difference between revisions

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{{STRUCTURE_2b6p|  PDB=2b6p  |  SCENE=  }}
===X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state===
{{ABSTRACT_PUBMED_15377788}}


==About this Structure==
==X-ray structure of lens Aquaporin-0 (AQP0) (lens MIP) in an open pore state==
[[2b6p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA].  
<StructureSection load='2b6p' size='340' side='right'caption='[[2b6p]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2b6p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B6P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2B6P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2b6p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2b6p OCA], [https://pdbe.org/2b6p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2b6p RCSB], [https://www.ebi.ac.uk/pdbsum/2b6p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2b6p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MIP_BOVIN MIP_BOVIN] Water channel. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core.<ref>PMID:16319884</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/2b6p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2b6p ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Aquaporin|Aquaporin]]
*[[Aquaporin 3D structures|Aquaporin 3D structures]]
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:015377788</ref><ref group="xtra">PMID:016319884</ref><references group="xtra"/>
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Cheng, Y.]]
[[Category: Large Structures]]
[[Category: Fujiyoshi, Y.]]
[[Category: Cheng Y]]
[[Category: Gonen, T.]]
[[Category: Fujiyoshi Y]]
[[Category: Harrison, S C.]]
[[Category: Gonen T]]
[[Category: Hiroaki, Y.]]
[[Category: Harrison SC]]
[[Category: Sliz, P.]]
[[Category: Hiroaki Y]]
[[Category: Walz, T.]]
[[Category: Sliz P]]
[[Category: Aqp0]]
[[Category: Walz T]]
[[Category: Aquaporin]]
[[Category: Aquaporin-0]]
[[Category: Lens mip]]
[[Category: Membrane protein]]
[[Category: Open water pore]]
Retrieved from "https://proteopedia.org/2b6p"