4jh4: Difference between revisions
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New page: '''Unreleased structure''' The entry 4jh4 is ON HOLD Authors: Thompson, M.K., Harp, J., Keithly, M.E., Jagessar, K., Cook, P.D., Armstrong, R.N. Description: Crystal Structure of FosB ... |
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==Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin== | |||
<StructureSection load='4jh4' size='340' side='right'caption='[[4jh4]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4jh4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus_ATCC_10987 Bacillus cereus ATCC 10987]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JH4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JH4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FCN:FOSFOMYCIN'>FCN</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jh4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jh4 OCA], [https://pdbe.org/4jh4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jh4 RCSB], [https://www.ebi.ac.uk/pdbsum/4jh4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jh4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FOSB_BACC1 FOSB_BACC1] Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity). | |||
==See Also== | |||
*[[Metallothiol transferase FosB|Metallothiol transferase FosB]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus cereus ATCC 10987]] | |||
[[Category: Large Structures]] | |||
[[Category: Armstrong RN]] | |||
[[Category: Cook PD]] | |||
[[Category: Harp J]] | |||
[[Category: Jagessar K]] | |||
[[Category: Keithly ME]] | |||
[[Category: Thompson MK]] | |||
Latest revision as of 12:03, 1 March 2024
Crystal Structure of FosB from Bacillus cereus with Nickel and Fosfomycin
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