4e46: Difference between revisions

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{{STRUCTURE_4e46|  PDB=4e46  |  SCENE=  }}
===Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol===


==About this Structure==
==Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol==
[[4e46]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E46 OCA].  
<StructureSection load='4e46' size='340' side='right'caption='[[4e46]], [[Resolution|resolution]] 1.26&Aring;' scene=''>
[[Category: Haloalkane dehalogenase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[4e46]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_rhodochrous Rhodococcus rhodochrous]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E46 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E46 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.26&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e46 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e46 OCA], [https://pdbe.org/4e46 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e46 RCSB], [https://www.ebi.ac.uk/pdbsum/4e46 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e46 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DHAA_RHORH DHAA_RHORH] Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Expresses halogenase activity against 1-chloroalkanes of chain length C3 to C10, and also shows a very weak activity with 1,2-dichloroethane.
 
==See Also==
*[[Dehalogenase 3D structures|Dehalogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Rhodococcus rhodochrous]]
[[Category: Rhodococcus rhodochrous]]
[[Category: Chaloupkova, R.]]
[[Category: Chaloupkova R]]
[[Category: Damborsky, J.]]
[[Category: Damborsky J]]
[[Category: Smatanova, I Kuta.]]
[[Category: Kuta Smatanova I]]
[[Category: Stsiapanava, A.]]
[[Category: Stsiapanava A]]
[[Category: Alpha/beta hydrolase fold]]
[[Category: Catalytic pentad]]
[[Category: Halide binding]]
[[Category: Hydrolase]]
[[Category: Hydrolytic dehalogenation]]

Latest revision as of 14:52, 14 March 2024

Structure of Rhodococcus rhodochrous haloalkane dehalogenase DhaA in complex with 2-propanol

4e46, resolution 1.26Å

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