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{{STRUCTURE_3hjn|  PDB=3hjn  |  SCENE=  }}
===Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima===


==About this Structure==
==Crystal structure of thymidylate kinase in complex with dTDP and ADP from Thermotoga maritima==
[[3hjn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2z0h 2z0h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HJN OCA].  
<StructureSection load='3hjn' size='340' side='right'caption='[[3hjn]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
[[Category: Thermotoga maritima]]
== Structural highlights ==
[[Category: DTMP kinase]]
<table><tr><td colspan='2'>[[3hjn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2z0h 2z0h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HJN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HJN FirstGlance]. <br>
[[Category: Kuramitsu, S.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
[[Category: Nakagawa, N.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TYD:THYMIDINE-5-DIPHOSPHATE'>TYD</scene></td></tr>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hjn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hjn OCA], [https://pdbe.org/3hjn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hjn RCSB], [https://www.ebi.ac.uk/pdbsum/3hjn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hjn ProSAT], [https://www.topsan.org/Proteins/RSGI/3hjn TOPSAN]</span></td></tr>
[[Category: Shirouzu, M.]]
</table>
[[Category: Yokoyama, S.]]
== Function ==
[[Category: Yoshikawa, S.]]
[https://www.uniprot.org/uniprot/KTHY_THEMA KTHY_THEMA]  
[[Category: Atp-binding]]
== Evolutionary Conservation ==
[[Category: Kinase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: National project on protein structural and functional analyse]]
Check<jmol>
[[Category: Nppsfa]]
  <jmolCheckbox>
[[Category: Nucleotide biosynthesis]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hj/3hjn_consurf.spt"</scriptWhenChecked>
[[Category: Nucleotide-binding]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Riken structural genomics/proteomics initiative]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Rsgi]]
  </jmolCheckbox>
[[Category: Structural genomic]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hjn ConSurf].
[[Category: Thymidylate kinase]]
<div style="clear:both"></div>
[[Category: Transferase]]
 
==See Also==
*[[Thymidylate kinase 3D structures|Thymidylate kinase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima MSB8]]
[[Category: Kuramitsu S]]
[[Category: Nakagawa N]]
[[Category: Shirouzu M]]
[[Category: Yokoyama S]]
[[Category: Yoshikawa S]]
Retrieved from "https://proteopedia.org/3hjn"