3ilf: Difference between revisions
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== | ==Crystal structure of porphyranase A (PorA) in complex with neo-porphyrotetraose== | ||
[[3ilf]] is a 1 chain structure with sequence from [ | <StructureSection load='3ilf' size='340' side='right'caption='[[3ilf]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3ilf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zobellia_galactanivorans Zobellia galactanivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ILF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ILF FirstGlance]. <br> | ||
< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GAL:BETA-D-GALACTOSE'>GAL</scene>, <scene name='pdbligand=GLA:ALPHA+D-GALACTOSE'>GLA</scene>, <scene name='pdbligand=L6S:6-O-SULFO-ALPHA-L-GALACTOSE'>L6S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ilf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ilf OCA], [https://pdbe.org/3ilf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ilf RCSB], [https://www.ebi.ac.uk/pdbsum/3ilf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ilf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PORA_ZOBGA PORA_ZOBGA] Cleaves the sulfated polysaccharide porphyran at the (1->4) linkages between beta-D-galactopyranose and alpha-L-galactopyranose-6-sulfate, forming mostly the disaccharide alpha-L-galactopyranose-6-sulfate-(1->3)-beta-D-galactose. Some longer oligosaccharides of even number of residues are also observed. Inactive on the non-sulfated agarose portion of the porphyran backbone. Displays a strict requirement for C6-sulfate in the -2 and +1-binding subsites.<ref>PMID:20376150</ref> <ref>PMID:22778272</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/il/3ilf_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ilf ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Zobellia galactanivorans]] | [[Category: Zobellia galactanivorans]] | ||
[[Category: Barbeyron | [[Category: Barbeyron T]] | ||
[[Category: Correc | [[Category: Correc G]] | ||
[[Category: Czjzek | [[Category: Czjzek M]] | ||
[[Category: Hehemann | [[Category: Hehemann JH]] | ||
[[Category: Helbert | [[Category: Helbert W]] | ||
[[Category: Michel | [[Category: Michel G]] | ||
Latest revision as of 08:28, 20 March 2024
Crystal structure of porphyranase A (PorA) in complex with neo-porphyrotetraose
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