4jk0: Difference between revisions
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New page: '''Unreleased structure''' The entry 4jk0 is ON HOLD Authors: Katorcha, E., Tamjar, J., Popov, A.N., Malinina, L. Description: Crystal structure of p19_T89Q in complex with double-heli... |
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==Crystal structure of T89Q-mutant of RNA silencing suppressor p19 with 2nt-5'-overhanging double-helical RNA 21mer pUUUG(CUG)5CU== | |||
<StructureSection load='4jk0' size='340' side='right' caption='[[4jk0]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4jk0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Tbsv Tbsv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JK0 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4jgn|4jgn]], [[4j39|4j39]], [[1r9f|1r9f]], [[4e48|4e48]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ORF4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=12145 TBSV])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jk0 OCA], [http://pdbe.org/4jk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jk0 RCSB], [http://www.ebi.ac.uk/pdbsum/4jk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jk0 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/P19_TBSVK P19_TBSVK]] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity). | |||
==See Also== | |||
*[[P19|P19]] | |||
*[[RNA silencing suppressor|RNA silencing suppressor]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Tbsv]] | |||
[[Category: Katorcha, E]] | |||
[[Category: Malinina, L]] | |||
[[Category: Popov, A N]] | |||
[[Category: Tamjar, J]] | |||
[[Category: Dimer]] | |||
[[Category: Protein-rna complex]] | |||
[[Category: Rna binding protein-rna complex]] | |||
[[Category: Rna silencing suppression]] | |||
[[Category: Trinucleotide repeat]] | |||
