2cop: Difference between revisions

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[[Image:2cop.gif|left|200px]]<br /><applet load="2cop" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2cop" />
'''Solution structure of RSGI RUH-040, an ACBP domain from human cDNA'''<br />


==About this Structure==
==Solution structure of RSGI RUH-040, an ACBP domain from human cDNA==
2COP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COP OCA].  
<StructureSection load='2cop' size='340' side='right'caption='[[2cop]]' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2cop]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2COP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2COP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cop OCA], [https://pdbe.org/2cop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cop RCSB], [https://www.ebi.ac.uk/pdbsum/2cop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cop ProSAT], [https://www.topsan.org/Proteins/RSGI/2cop TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACBD6_HUMAN ACBD6_HUMAN] Binds long-chain acyl-coenzyme A molecules with a strong preference for unsaturated C18:1-CoA, lower affinity for unsaturated C20:4-CoA, and very weak affinity for saturated C16:0-CoA. Does not bind fatty acids.<ref>PMID:18268358</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/co/2cop_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cop ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Hayashi, F.]]
[[Category: Hayashi F]]
[[Category: Hirota, H.]]
[[Category: Hirota H]]
[[Category: Momen, A Z.M Ruhul.]]
[[Category: Ruhul Momen AZM]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: acyl coa binding protein]]
[[Category: coa binding protein]]
[[Category: lipid binding protein]]
[[Category: national project on protein structural and functional analyses]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:50:52 2008''

Latest revision as of 11:27, 22 May 2024

Solution structure of RSGI RUH-040, an ACBP domain from human cDNA

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