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[[Image:2cz8.gif|left|200px]]<br /><applet load="2cz8" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2cz8, resolution 1.50&Aring;" />
'''Crystal Structure of tt0972 protein from Thermus thermophilus'''<br />


==About this Structure==
==Crystal Structure of tt0972 protein from Thermus thermophilus==
2CZ8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=FAD:'>FAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ8 OCA].
<StructureSection load='2cz8' size='340' side='right'caption='[[2cz8]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Thermus thermophilus]]
<table><tr><td colspan='2'>[[2cz8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZ8 FirstGlance]. <br>
[[Category: Inagaki, E.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
[[Category: Kumei, M.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Nakano, N.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cz8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cz8 OCA], [https://pdbe.org/2cz8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cz8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cz8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cz8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cz8 TOPSAN]</span></td></tr>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
</table>
[[Category: Shinkai, A.]]
== Function ==
[[Category: Yokoyama, S.]]
[https://www.uniprot.org/uniprot/DODEC_THET8 DODEC_THET8] May function as storage protein that sequesters various flavins and other cofactors, thereby protecting the cell against undesirable reactions mediated by the free cofactors. Binds and sequesters FMN, FAD, lumiflavin and lumichrome, and can also bind coenzyme A.<ref>PMID:17855371</ref>
[[Category: FAD]]
== Evolutionary Conservation ==
[[Category: K]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: PO4]]
Check<jmol>
[[Category: dodecamer]]
  <jmolCheckbox>
[[Category: flavin]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2cz8_consurf.spt"</scriptWhenChecked>
[[Category: flavin-adenine dinucleotide]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: national project on protein structural and functional analyses]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: nppsfa]]
  </jmolCheckbox>
[[Category: riken structural genomics/proteomics initiative]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cz8 ConSurf].
[[Category: rsgi]]
<div style="clear:both"></div>
[[Category: structural genomics]]
== References ==
 
<references/>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:53:48 2008''
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermus thermophilus HB8]]
[[Category: Inagaki E]]
[[Category: Kumei M]]
[[Category: Nakano N]]
[[Category: Shinkai A]]
[[Category: Yokoyama S]]
Retrieved from "https://proteopedia.org/2cz8"