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[[Image:2czc.gif|left|200px]]<br /><applet load="2czc" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2czc, resolution 2.00&Aring;" />
'''Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Pyrococcus horikoshii OT3'''<br />


==About this Structure==
==Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Pyrococcus horikoshii OT3==
2CZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glyceraldehyde-3-phosphate_dehydrogenase_(NAD(P)(+))_(phosphorylating) Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.59 1.2.1.59] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZC OCA].
<StructureSection load='2czc' size='340' side='right'caption='[[2czc]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating)]]
== Structural highlights ==
[[Category: Pyrococcus horikoshii]]
<table><tr><td colspan='2'>[[2czc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CZC FirstGlance]. <br>
[[Category: Single protein]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: Arai, R.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
[[Category: Ito, K.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2czc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2czc OCA], [https://pdbe.org/2czc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2czc RCSB], [https://www.ebi.ac.uk/pdbsum/2czc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2czc ProSAT], [https://www.topsan.org/Proteins/RSGI/2czc TOPSAN]</span></td></tr>
[[Category: Kamo-Uchikubo, T.]]
</table>
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
== Function ==
[[Category: Shirouzu, M.]]
[https://www.uniprot.org/uniprot/G3P_PYRHO G3P_PYRHO]  
[[Category: Yokoyama, S.]]
== Evolutionary Conservation ==
[[Category: NAD]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: PO4]]
Check<jmol>
[[Category: glycolysis]]
  <jmolCheckbox>
[[Category: nad]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cz/2czc_consurf.spt"</scriptWhenChecked>
[[Category: national project on protein structural and functional analyses]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: nppsfa]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: oxidoreductase]]
  </jmolCheckbox>
[[Category: riken structural genomics/proteomics initiative]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2czc ConSurf].
[[Category: rsgi]]
<div style="clear:both"></div>
[[Category: structural genomics]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:53:52 2008''
==See Also==
*[[Glyceraldehyde-3-phosphate dehydrogenase 3D structures|Glyceraldehyde-3-phosphate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Arai R]]
[[Category: Ito K]]
[[Category: Kamo-Uchikubo T]]
[[Category: Shirouzu M]]
[[Category: Yokoyama S]]

Latest revision as of 08:21, 25 October 2023

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Pyrococcus horikoshii OT3

2czc, resolution 2.00Å

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