2d4v: Difference between revisions

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[[Image:2d4v.gif|left|200px]]<br /><applet load="2d4v" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2d4v, resolution 1.90&Aring;" />
'''Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans'''<br />


==About this Structure==
==Crystal structure of NAD dependent isocitrate dehydrogenase from Acidithiobacillus thiooxidans==
2D4V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Acidithiobacillus_thiooxidans Acidithiobacillus thiooxidans] with <scene name='pdbligand=FLC:'>FLC</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4V OCA].  
<StructureSection load='2d4v' size='340' side='right'caption='[[2d4v]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[2d4v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Acidithiobacillus_thiooxidans Acidithiobacillus thiooxidans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D4V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D4V FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d4v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d4v OCA], [https://pdbe.org/2d4v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d4v RCSB], [https://www.ebi.ac.uk/pdbsum/2d4v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d4v ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8GAX0_ACITH Q8GAX0_ACITH]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d4/2d4v_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d4v ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Isocitrate dehydrogenase 3D structures|Isocitrate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Acidithiobacillus thiooxidans]]
[[Category: Acidithiobacillus thiooxidans]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Imada, K.]]
[[Category: Imada K]]
[[Category: Inagaki, K.]]
[[Category: Inagaki K]]
[[Category: Namba, K.]]
[[Category: Namba K]]
[[Category: Tamura, T.]]
[[Category: Tamura T]]
[[Category: FLC]]
[[Category: NAD]]
[[Category: alpha and beta protein]]
[[Category: isocitrate/isopropylmalate dehydrogenase-like fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:55:22 2008''
Retrieved from "https://proteopedia.org/2d4v"